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Meta-analysis of the clinical effect of traditional Chinese medicine technique intervention in female perimenopausal insomnia |
WEN Qianqian1, XING Yadan2, CAO Muyuan3, DU Caifeng2, WANG Li4, ZHAO Yong1 |
1. The Second Hospital of Shanxi Medical University, Taiyuan 030001, China; 2. School of Nursing, Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China; 3. School of Basic Medicine, Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China; 4. The First Clinical College of Shanxi University of Traditional Chinese Medicine, Jinzhong 030619, China; 5. Department of Neonatology, Shanxi Bethune Hospital, Taiyuan 030032, China |
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Abstract Objective To systematically describe and analyze the effectiveness of traditional Chinese medicine technique in the intervention of perimenopausal insomnia, and to provide some reference for clinical practice. Methods The databases of PubMed, Web of science, Cochrane Library, China Biomedical Database, CNKI, Wanfang and VIP were searched by computer from January 2003 to December 31, 2022. Randomized controlled trials on the intervention of TCM techniques in perimenopausal insomnia were included, and statistical analysis was performed using RevMan5.3 software. Results A total of 21 articles were included, involving 1809 patients. The results of meta-analysis showed that the clinical efficacy of Chinese medicine intervention in perimenopausal insomnia in the experimental group and the control group was significantly improved (OR=4.01, 95%CI: 2.89-5.57, P<0.05), and Pittsburgh sleep quality (MD=-2.52, 95%CI: There were significant effects in -3.29~ -1.75, P<0.05], anxiety (SMD=-0.69, 95%CI: -0.90~-0.48, P<0.05), depression (MD=-6.56, 95%CI: -8.10~-5.02, P<0.05). There were no significant differences in E2(MD=2.21, 95%CI: -1.62~6.03, P>0.05) and FSH (MD=0.20, 95%CI=-0.43~0.03, P>0.05). Conclusion Chinese medicine technology can improve the sleep quality of perimenopausal insomnia patients, and also has a certain effect on the anxiety and depression of perimenopausal insomnia women, and Chinese medicine technology is safe, worthy of clinical promotion.
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Received: 07 March 2023
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