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| Effect of continuous intravenous infusion of oxytocin combined with sufentanil analgesia pump on the analgesic effect and postoperative anxiety of patients undergoing laparoscopic myomectomy |
| ZHU Changwei1, ZHANG Jingchao1, XU Xianhua2 |
1. Suzhou First People's Hospital, Suzhou 234009, China;
2. Xianyang Hospital, Yan'an University, Xianyang 71200, China; |
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Abstract Objective To investigate the effect of continuous intravenous infusion of oxytocin combined with sufentanil analgesia pump on the analgesic effect and postoperative anxiety of patients undergoing laparoscopic myomectomy. Methods 80 patients with uterine fibroids admitted to the first people's Hospital of Suzhou City from August 2019 to August 2021 were selected and randomly divided into observation group and control group, 40 cases each. The control group was treated with sufentanil alone and the observation group was treated with oxytocin combined with sufentanil. The analgesic effect of the two groups, the Ramsay score, the VAS score and the HAD score at each time point, and the total incidence of postoperative adverse reactions were compared. Results The excellent rate of analgesia in the observation group was 97.50%, higher than that in the control group (75.00%). The Ramsay scores of the two groups were similar at 1 h and 48 h after operation, and the Ramsay scores of the observation group at 12 h and 24 h after operation were significantly higher than those of the control group. VAS score and had score in the observation group were lower than those in the control group at 12 h, 24 h and 48 h after operation. The adverse reactions in control group (25.00%) was higher in the observation group (7.50%). Conclusion Oxytocin combined with sufentanil analgesia pump continuous pumping for postoperative analgesia in patients undergoing laparoscopic myomectomy can achieve good analgesia and sedative effect, superior to sufentanil alone, and can effectively inhibit Inflammatory response and anxiolytic, and with the decrease in sufentanil concentration, the adverse reactions are reduced.
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Received: 02 September 2022
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| Cite this article: |
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ZHU Changwei,ZHANG Jingchao,XU Xianhua. Effect of continuous intravenous infusion of oxytocin combined with sufentanil analgesia pump on the analgesic effect and postoperative anxiety of patients undergoing laparoscopic myomectomy[J]. HuNan ShiFan DaXue XueBao(YiXueBan), 2023, 20(2): 89-92.
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| URL: |
| http://yxb.hunnu.edu.cn/EN/ OR http://yxb.hunnu.edu.cn/EN/Y2023/V20/I2/89 |
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[2] 刘晓忠. 催产素联合舒芬太尼对腹腔镜子宫肌瘤剔除术患者镇痛效果及术后心理状况的影响[J]. 浙江临床医学, 2021, 23(2): 277-278+281.
[3] 陈耘, 闫桂敏, 朱海, 等. 硬膜外分娩镇痛对催产素引产孕妇妊娠结局的影响[J]. 外科研究与新技术, 2020, 9(4): 257-259+270.
[4] 张之翠, 韩振华, 方芳, 等. 丙泊酚联合舒芬太尼麻醉致无痛清宫术患者术中记忆的调查[J]. 药物不良反应杂志, 2020, 22(5): 295-299.
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[6] 张晓宇. CAT与HAD对慢性阻塞性肺疾病稳定期患者认知度干预后焦虑和抑郁状态评价临床研究[J]. 国际呼吸杂志, 2020, 40(14): 1067-1072.
[7] 金文英, 周南. 地佐辛复合舒芬太尼用于腹腔镜子宫肌瘤剔除术术后镇痛的有效性和安全性[J]. 实用药物与临床, 2018, 21(10): 94-96.
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[14] 谢玉兰, 刘文松, 彭明. 中药镇痛方对四肢骨折疼痛效果及血清CRP、TNF-α水平影响的研究[J]. 中国医学创新, 2019, 16(14): 103-107.
[15] 廖媛. 孕足月低位水囊引产联合静滴缩宫素对产妇血清WBC、CRP水平的影响[J]. 现代医学与健康研究电子杂志, 2020, 4(4): 34-36.
[16] 罗义华, 张贵清, 邓尚莉, 等. 中西医结合护理对育龄期腹腔镜子宫肌瘤剔除术患者焦虑情绪及胃肠功能恢复的影响[J]. 临床与病理杂志, 2022, 42(2): 421-426.
[17] 李鑫, 吴秀英. 羟考酮与舒芬太尼用于腹腔镜辅助全子宫切除术术后镇痛的效果比较[J]. 中国医科大学学报, 2019, 48(5): 64-67. |
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2023, Vol. 20 
