Abstract：Objective To analyze the diagnostic value in patients with chronic obstructive pulmonary disease by CT-guided percutaneous lung biopsy and bronchoscopy. Methods Since August 2012 to November 2014 in our hospital 69 patients (45 cases were male, female 24 cases), preclude the use of CT-guided percutaneous lung biopsy, bronchoscopy, diagnosed with chronic obstructive pulmonary lung disease, comparing both the sensitivity and specificity, and X2 test, observe their effect. Results (1) 33 cases with fiber bronchoscope examination in patients with 1 cases of pneumothorax, bleeding occurred in 1 cases during inspection, no other complications, the overall complication rate was 6.1%. 36 cases of CT guided percutaneous lung biopsy in patients with 5 cases of complications, the total occurrence rate is 13.9%. 3 cases of pneumothorax, hemoptysis in 1 cases, 1 cases of hemothorax. Comparison of two groups of methods, percutaneous lung biopsy is significantly higher than that of fiberoptic bronchoscopy, with significant difference. (2) the pathological findings as the gold standard for the diagnosis for large amount of purulent sputum obstruction in 35 cases, sputum embolism formation and obstruction in 33 cases, the diagnosis of total diagnosis rate was 95.55% (the total number of cases of confirmed cases of D / 100%). Fiberoptic bronchoscopy in the diagnosis of sensitivity, specificity, positive predictive value, and negative predictive value (NPV) and accuracy were 90%, 100%, 100%, 96.7%, and 97.4%. Percutaneous lung puncture, their values were 70%, 59.8%, 37.5%, 85.2%, and 62.4% (P=0.052; P<0.001, P<0.001; P=0.011; P<0.001). A lot of phlegm obstruction (35 cases) the accuracy rate of diagnosis, fiber bronchoscope accurate rate is higher than the percutaneous lung biopsy (94.6% vs. 77.8%; P=0.044). The blockage and sputum bolt form (33 cases) the accuracy rate of diagnosis, fiberoptic bronchoscopy and percutaneous lung puncture the same high (97.9% vs. 96.3%; P=0.689).Conclusion Both examination methods in the diagnosis of lung disease on different clinical value in clinical organically combine them, to the greatest extent possible to reduce the rate of misdiagnosis and misdiagnosis rate, and can get good treatment.
2015,Vol. 12
