水刀系统清创术联合真空辅助闭合技术治疗对糖尿病足溃疡患者临床疗效、创面愈合及血流动力学的影响

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摘要目的：探讨水刀系统清创术联合真空辅助闭合技术（VAC）治疗对糖尿病足溃疡患者临床疗效、创面愈合及血流动力学的影响。方法：选取2019年6月―2021年6月本院收治的123例糖尿病足溃疡患者,按照随机平行对照研究法将其分为对照组64例（水刀系统清创术）、观察组59例（水刀系统清创术+真空辅助闭合技术）。对比两组治疗疗效、创面愈合情况、血流动力学指标及术后6个月复发率。结果：观察组总有效率94.92%高于对照组79.69%;治疗后,两组溃疡面积缩小,创面氧分压升高,创面pH值下降,观察组创面愈合指标更好;治疗后,两组血流速度、血管内径、阻力指数（RI）、搏动指数（PI）均升高,且观察组高于对照组;对照组复发率显著高于观察组。结论：水刀系统清创术联合VAC治疗糖尿病足溃疡,在改善血流动力学指标、降低复发率等方面优势较大。

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	刘淑岩

关键词：水刀系统清创术,真空辅助闭合技术,糖尿病足溃疡,临床疗效,创面愈合,血流动力学

Abstract：ObjectiveTo investigate the effects of waterknife system defibrillation combined with vacuum assisted closure (VAC) on clinical efficacy, wound healing and hemodynamics of diabetic foot ulcer patients.Methods123 patients with diabetic foot ulcers admitted to our hospital from June 2019 to June 2021, and according to the randomized parallel control study, they were divided into the control group of 64 cases (water knife system debridement) and the observation group of 59 cases (water knife system debridement+vacuum assisted closure technology). Therapeutic efficacy, wound healing, hemodynamic indexes and recurrence rate 6 months after operation were compared between the two groups.ResultsThe total effective rate of observation group was 94.92% higher than 79.69% of control group; after treatment, the ulcer area in the two groups decreased, the partial pressure of oxygen in the wound increased, and the pH value of the wound decreased, and the wound healing index in the observation group was better; after treatment, blood flow velocity, inner diameter of blood vessels, resistance index (RI) 、pulse index (PI) in the two groups were increased, and the above indexes in the observation group were higher than those in the control group; the recurrence rate in the control group was significantly higher than that in the observation group (26.56% VS 8.47%).ConclusionWater jet system debridement combined with VAC in the treatment of diabetic foot ulcer has great advantages in improving hemodynamic indexes and reducing recurrence rate.

Key words：water knife debridement vacuum assisted closure diabetic foot ulcer clinical efficacy wound healing hemodynamics

收稿日期:2022-05-05

中图分类号:

R587.1

通讯作者:刘淑岩,E-mail：l18031528229@163.com

引用本文:

刘淑岩. 水刀系统清创术联合真空辅助闭合技术治疗对糖尿病足溃疡患者临床疗效、创面愈合及血流动力学的影响[J]. journal1, 2023, 20(2): 101-103. LIU Shuyan. Effects of water knife system debridement combined with vacuum assisted closure on clinical efficacy, wound healing and hemodynamics of diabetic foot ulcer. journal1, 2023, 20(2): 101-103.

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http://yxb.hunnu.edu.cn/CN/或http://yxb.hunnu.edu.cn/CN/Y2023/V20/I2/101

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