Abstract:Objective To investigate the effects of comprehensive health management on delivery outcome of pregnant women with Gestational diabetes mellitus in Zhuzhou area. Methods A total of 100 pregnant women who were diagnosed as gestational diabetes mellitus by 75g oral glucose tolerance test during week 24-28 of gestation were enrolled in the study. There were 50 cases in Experimental group who voluntarily undergo integrated health management and 50 cases in control group who except voluntary general nursing intervention. The self-management and pregnancy outcome of the two groups were observed. Results The self-management efficacy scores of the experimental group were significantly higher than those of the control group, and the scores of diet control, regular exercise and blood glucose monitoring were higher than those of the control group, There was no significant difference in foot care, blood glucose treatment and compliance with medical drugs. The qualified rate of body quality control in the experimental group was higher than that in the control group, the number of people using insulin was less than that in the control group, and the postprandial blood glucose in the experimental group was lower than that in the control group, the difference was statistically significant. There was no significant difference in HBA1c and fasting blood glucose between the two groups. The incidence of pregnancy-induced hypertension, cesarean section, postpartum hemorrhage, neonatal asphyxia, neonatal hypoglycemia and macrosomia in the experimental group was lower than that in the control group, and the difference was statistically significant. Conclusion The comprehensive health management model is beneficial to improve the compliance of pregnant women with gestational diabetes mellitus, effectively reduce the occurrence of cesarean section, neonatal hypoglycemia, asphyxia and huge fever, improve the pregnancy outcome, and has good clinical promotion value.