Abstract：Abstract: Islet cells are a type of islet β cells, which belong to endocrine cells. Their main physiological function is to secrete insulin to cope with an increase in glucose levels, and therefore, they play an impor-tant role in maintaining glucose homeostasis. Studies have shown that insulin secretion is regulated by a va-riety of mechanisms, including multiple ion channels. In recent years, scholars have paid more and more at-tention to the process of regulating insulin secretion by ion channels. Herein, the regulation of insulin secre-tion by sodium, potassium and calcium ion channels and the interaction among the three ion channels are discussed. Meanwhile, the use of ion channel inhibitors and the prospect of ion channel research in diabetes treatment are briefly described.
引用本文:
孙慧珍, 雷水红, 龚妍春, 姚丽华. 离子通道对胰岛β细胞中胰岛素分泌的调控作用[J]. 生命科学研究, 2022, 26(1): 59-66. SUN Hui-zhen, LEI Shui-hong, GONG Yan-chun, YAO Li-hua. Regulation of Ion Channels on Insulin Secretion in Islet β Cells. Life Science Research, 2022, 26(1): 59-66.
