Abstract：Abstract: Kinesin is one kind of molecular motor, and also a nucleotidase. This kind of protein can convert the chemical energy from ATP hydrolysis to mechanical energy to power its processive movement along microtubule with one ATP molecule per step. How kinesin transforms chemical energy to mechanical energy is a hot issue in the field of biophysics. The studies related to kinesin’s energy conversion are reviewed herein from three aspects: binding of ATP molecule to kinesin, motor-head rotation induced by ATP binding, and kinesin neck-linker docking caused by motor-head rotation. Kinesin’s energy-conversion pathway is the combination of these three aspects.
引用本文:
马翼龙, 李 铁, 吕丽娜, 耿轶钊, 纪 青. 驱动蛋白的能量转换过程 ——从ATP分子结合到颈链对接[J]. 生命科学研究, 2019, 23(5): 425-430. MA Yi-long, LI Tie, Lü Li-na, GENG Yi-zhao, JI Qing. Process of Kinesin’s Energy Conversion ——from ATP Binding to Neck Linker Docking. Life Science Research, 2019, 23(5): 425-430.
