Abstract：Abstract: Breast cancer is one of the most common cancers that lead to death in women worldwide. At present, chemotherapy is still an important means of systemic treatment of breast cancer besides the surgical treatment. But poor prognosis, short survival and fast recurrence affect the therapeutic effect. With the development of the signaling pathways and cell apoptosis in the tumor research, targeted therapy against main signaling pathways of breast carcinogenesis has become a focus of anti-tumor research, and some progress has been made in the treatment of breast cancer. In recent years, studies found that acetylcholine receptors are correlated with the occurrence and development of many diseases, especially tumors. Therefore, alpha-conotoxins, as a specific antagonist of the acetylcholine receptor, may become a novel targeted therapy drug for breast cancer.
引用本文:
孙志华, 邴 晖, 刘益巧, 钱 江, 长孙东亭, 罗素兰. 乳腺癌靶向治疗的研究进展[J]. 生命科学研究, 2017, 21(3): 275-282. SUN Zhi-Hua, BING Hui, LIU Yi-Qiao, QIAN Jiang, CHANG Sun-Dong-Ting, LUO Su-Lan. Progresses on Targeted Therapy for Human Breast Cancer. Life Science Research, 2017, 21(3): 275-282.
2017,Vol. 21
