Abstract：Abstract: The WRAP53β protein, an important member of the WD40 protein family, controls intracellular trafficking of telomerase, DNA repair proteins and the splicing factors, and is also involved in the formation of Cajal body, telomere stability and elongation. Dysfunction of this protein has been associated with premature aging, cancer and neurodegeneration, and this suggests that WRAP53β will be a potential molecular target in treatment of diseases. Here, the multifaceted molecular functions of WRAP53β and its research progress in diseases were reviewed.
引用本文:
陈洁莹, 孙 洋, 杨 潮, 李江林, 叶 茂. WRAP53β的分子功能及其在疾病中的作用[J]. 生命科学研究, 2017, 21(3): 257-261. CHEN Jie-Ying, SUN Yang, YANG Chao, LI Jiang-Lin, YE Mao. Molecular Function of WRAP53β and Its Role in Diseases. Life Science Research, 2017, 21(3): 257-261.
2017,Vol. 21
