姓名：李俊男

照片：

职称：讲师

电子邮箱：lijunnan0509@126.com

个人简介：李俊男，女，汉族，硕士生导师。2023年毕业于澳门大学，获得生物医药专业博士学位, 同年7月加入金宝搏官方188医学院药学系和“小分子靶向药物研究与创制”湖南省重点实验室。现主持湖南省自然科学青年基金项目一项。主要从事肺癌肿瘤耐药的治疗及其机制的研究，通过建立EGFR-TKIs耐药细胞系，对耐药机制进行深入探索并且设计不同的联合手段进行逆转耐药的研究。近年在Drug Resistance Updates, Cellular and Molecular Life Sciences等国际知名期刊发表SCI论文数篇，其中第一作者（包含共同一作）共计5篇。

代表学术性论文：

(1)Junnan Li;Lipeng Zhu; Hang Fai Kwok; Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment, Drug Resistance Updates, 2023, 66: 100904

(2)Junnan Li;Pengchen Chen; Qiushuang Wu; Libin Guo; Ka Weng Leong; Kin Iong Chan; Hang Fai Kwok; A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis, Cellular and Molecular Life Sciences, 2022, 79(12): 614

(3)Junnan Li;Hongwei Du; Meishuang Zhang; Zhi Zhang; Fei Teng; Yali Zhao; Wenyou Zhang; Yang Yu; Linjing Feng; Xinming Cui; Ming Zhang; Tzongshi Lu; Fengying Guan; Li Chen; Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells, International Journal of Biological Sciences, 2019, 15(7): 1533-1545

(4)Junnan Li;Hang Fai Kwok; Current Strategies for Treating NSCLC: From Biological Mechanisms to Clinical Treatment, Cancers, 2020, 12(6): 1587

(5) Lipeng Zhu^#;Junnan Li^#;Ziang Guo; Hang Fai Kwok; Qi Zhao; Synergistic combination of targeted nano-nuclear-reactors and anti-PD-L1 nanobodies evokes persistent T cell immuneactivation for cancer immunotherapy, Journal of Nanobiotechnology, 2022, 20(1): 521

(6) Qiushuang Wu, ChenPeng Chen,Junnan Li,et al. Inhibition of bladder cancer growth with Homoharringtonine by inactivating integrin α5/β1-FAK/Src axis: A novel strategy for drug application. Pharmacological Research 188: 106654.

(7) Yang Yu, Linjing Feng,Junnan Li,Xiaoxin Lan,et al. The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits. Behavioural Brain Research. 2017;334:155-162.

(8)李俊男，于洋，杜红伟胰岛β细胞退分化在β细胞功能衰竭中的作用 中国病理生理杂志2018