Deciphering the Intricacies of Microbial Influence on Tumor Initiation and Progression within the Tumor Microenvironment: Unveiling Molecular Mechanisms
Abstract：Abstract: The tumor microenvironment comprises a multifaceted ecosystem encompassing a dynamic interplay between malignant cells, non-neoplastic counterparts, extracellular matrix constituents, and intricate microbial communities. In particular, microorganisms have established a pervasive presence within tumor masses, exhibiting a marked predilection for distinct spatial niches. The intricate amalgamation of their composition and multifaceted functional profiles assumes a commanding role in orchestrating the intricate ballet of tumor genesis and advancement. In this comprehensive review, we endeavor to illuminate the intricacies of intratumoral microbiota, unraveling the intricate molecular mechanisms that underpin its profound influence on the initiation and relentless progression of neoplastic growth. By doing so, we unveil a panorama of novel perspectives that hold promise in revolutionizing both diagnostic paradigms and therapeutic modalities for tumors. Key words: tumor; tumor microenvironment; microbe; microbial community; oncology treatment （Acta Laser Biology Sinica, 2023, 32(5): 385-392）
引用本文:
李隆杰，柯章敏，刘怡婷，李 丽，张允雷，张秀伟. 肿瘤微环境中微生物影响肿瘤发生发展的分子机制[J]. 激光生物学报, 2023, 32(5): 385-392. LI Longjie, KE Zhangmin, LIU Yiting, LI Li, ZHANG Yunlei, ZHANG Xiuwei. Deciphering the Intricacies of Microbial Influence on Tumor Initiation and Progression within the Tumor Microenvironment: Unveiling Molecular Mechanisms. journal1, 2023, 32(5): 385-392.
